Actually, the best possible sound
would be obtained by mounting the speakers at ear level, pointing directly at your ears, & equal distance from your ears. (assuming that the speakers were designed to be used "on-axis". Most computer speakers are. Most car speakers are not.) Having the subwoofer equal distance from your ears would also keep the sound from "smearing" around the crossover point, but that is getting way too picky for an arcade cab IMHO.
As far as music goes, is it important that the jukebox sound amazing for exactly
one person, standing directly in front of it.

I can't see myself standing in the sweet spot in front of an arcade machine, just to listen to music (unless maybe I'm playing games at the same time).
I'd put the arcade speakers where arcade speakers go & run another line out to a home stereo receiver with speakers placed high on the walls around the room (think nightclub or bar). Keep the arcade experience an arcade experience & the jukebox experience be an experience for everyone.
That being said, I was very picky when I mounted the speakers in my driving cab. They are at ear level.
It does give an extra "immersive" quality to the experience.
But then again, that's where the original speakers were on the cab I used (Virtual-On...same cab as Daytona USA)
Experiment, experiment, experiment!