UPDATE:
So, if you like Fallout 2, you will LOVE this game. It plays pretty much EXACTLY the same, with far more detail, options, flexibility, etc, as well as a different story of course.
You control 4 characters in your party, and more can join (I think 2 more, but maybe 3). You have no restrictions on how you allocated your points in character creation, but you can't do everything even with a perfectly rounded team, and the more you try to be a "jack of all trades", the more you lose out on being strong in any one area.
There are 3 skills for conversations that can come into play, and conversations can alter the direction of the game. You can take skills in "Kiss Ass", "Kick Ass", and "Smart Ass", and throughout conversations if you are highlighting a player with one of these skills, you will get options to use those skills and potentially change the conversation outcome. The higher your skill, the more likely a favorable outcome. Your personality will come into play here. There are other choices that can alter the way the game goes. I have not explored this enough to know how much impact, a lot of choices even early on.
There are different modes of difficulty, and it looks like one of the factors is whether conversations will point out key words or not. You can type different key words when conversing and end up with different results. In the rookie mode, these are highlighted in the conversation and you can just click to respond, but I believe as you jack up the level, you have to manually type your responses and the key words aren't highlighted. Your skills might also play a role in what gets highlighted in a conversation, not sure yet.
There are a lot of weapon choices, and you have to decide if you want to focus on one type, which is interesting when you have no experience in the game, so you might allocate points in skills you don't end up needing and suffer in other areas. There are some "prerolled" characters you can use, or you can just create your own (or mix and match for your 4 player team).
Combat is turn based and uses action points just like Fallout 2. Range plays a major role, as does positioning. Friendly fire is completely possible (particularly with shotguns and explosives) so there is a lot of strategy in fights. It takes action points to reload, to move, and to use an item. There are pain pills to heal a little that anyone can use, there are med packs that a character with field medic skills can use on themselves or others that are more effective, and there are surgeon skills for players who are incapacitated or bleeding. Resources are fairly scarce so you have to conserve where you can. You can avoid battles in some cases, and even kick fights off by taking a first shot (which puts you into battle mode)
If you like to explore and loot, there is plenty of that. There are even skills you can take to help with perception and pick out stuff you might miss. The view is "isometric" but you can zoom out to a full overhead view or in to a third person "over the shoulder" view. I chose about halfway for the classic 3/4 overhead view. The graphics are very good, and there is a special sound driver that you can install that uses psycho-acoustics to turn even stereo speakers (or headphones) into 7.1 surround. I turned on 5.1 and so far the ambient sounds are pretty darn good. I am temped to turn off the lights while I play just to immerse myself more.
There are quite a few skills you can take, and only so many points. So far I haven't noticed a correlation between attributes and skills, so I am not sure they come into play (I don't think they do). So Intelligence doesn't add to your ability to crack a safe better. But Intelligence gives you more skill points per level to allocate. You can take lockpicking, safecracking, explosives (trap disarming), computer science (hacking), mechanical repair, toaster repair, and a few others. And ALL come into play regularly, which makes it hard to choose what to focus on (or if to be a "jack of all trades"). There are critical failures, which can permanently disable something you are trying to get past. But say you critically fail on a lock pick, it jams it up, but if you have a character with mechanical repair, he can repair the lock and you can pick it again. Perception skill allows you to better spot traps, loot, etc.
There are other skills, like animal whisperer that allows you to befriend animals and some will even join you and give added benefits to the group. But be careful with shotguns, it is easy to accidentally shoot your own animal friends in a fight, lol. (oops) Water plays a big role in traveling, so having a character with the skills to find water is good. There are other skills that I haven't even investigated yet.
You can also do weaponsmithing, and when you find weapons you can sell them or break them down and possibly get upgrades that a weaponsmith can install on a weapon and make it better/different.
I played from 8 pm until 1:30 am last night, and it was WAY too easy to lose track of time (I am dragging ass this morning). You can save at any point, except when in battle. So you need to remember to save after any point you want don't want to lose progress. I believe when you leave a major area it autosaves, so if you forget you might not lose too much after a failed battle.
This is such a throwback to a great game style that I particularly enjoy. The action can be fast paced or you can take your time to strategize. It is a role playing game, so you need to enjoy character building and there is a fair amount of "spreadsheet" gaming (ie what works against what), and there is a LOT of reading. You can enable text to speech, but I haven't done that yet to see how good or bad it is. I am hooked on this game, and I know it doesn't bode well for me for the next few weeks at least. A lot of things are going to get put on the backburner to allow me to play, lol. I am OK with that, it has been a while since a game really captured my attention like this.