I'm not crazy for the MK layout either.
For anyone reading who doesn't know the difference, SF is 6 buttons, 3 on 2 rows like this:
() () ()
() () ()
While MK is like this (correct me if I'm wrong it's been a while):
() ()
()
() ()
Block is the middle button, the rest are punch and kick buttons.
It is actually a sort of neat idea, but I feel it doesn't work for very many games, where as 6 buttons on 2 rows works on most games, especially fighters.
If you also want to play neo-geo games, consider putting in another button on the SF layout, this has been talked to death and most people end up doing it. Like this:
() () ()
() () ()
() <- Extra button here so you have the 4 button neo-geo layout.
This setup is IMO the most flexible, the only downside is there are enough buttons that some guests will always ask what buttons they need to use for each game and the extra buttons get in the way of button masher games like track and field.