Is there a comprehensive list of films based on, inspired by, or heavily related to gaming?  If not, let me be the first one to start....right now:
Bloodrayne
Double Dragon
Grandma's Boy
Tron 
Nightmares: Bishop of Battle Chapter
Last Starfighter
Cloak & Dagger
House of the Dead
Resident Evil I+II
Pokemon
Alone in the Dark
Final Fanstasy
Mortal Kombat I+II
Street Fighter
Wing Commander
Tomb Raider 
Joysticks
The Wizard
Super Mario Brothers
Wargames(maybe)
Krull
Doom
Also, if anyone can think of T.V. shows as well:
Pac-Man
Starcade
Dragon's Lair
Pokemon 
