I like many aspects of your cabinet, good work so far!

Yor finishing details are nice with the rounded edges everywhere..
Few things I would reconsider though;
Reduce the amount of overhang on your control panel. The overage has no purpose, and just makes the monitor look smaller. If it was usable surface area, that would be different....
Player 2's button layout should be rotated slightly counter-clockwise, or it may be VERY uncomfortable to play when standing side by side. Since P2 stands slightly right of center, his right hand will have to rotate uncomfortably to the right to compensate for standing off-square, causing a hard bend at the wrist. I figured I'd at least mention this since you haven't drilled anything yet. I understand that symmetry is 'pretty', but with an 8-button layout, you really should reconsider your ergonomics a bit more (especially if you plan on bringing these to market). There is also too much spacing between the buttons. You would need GIANT hands to take advantage of your current layout. You also need to move player 1&2 further apart. It looks like there is only about an inch between P1's buttons and P2's joystick...That will make you sorry.
Have you ever visited slagcoin.com? they have great layout templates there...