I've tried pressing TAB when the game is running to alter the controls. It doesn't work... the joystick is simply not being registered when Mame is running.
I've tried looking in my Mame.ini file too but there is no "core input options" listed. I've tried searching for this problem on Google and I keep seeing people saying go into
Options > Default Game Options > Enable Joystick. Is this Mame32 they are talking about because I can't find this anywhere.
I just want to globally enable the U360 to all games as default. Then I just have to upload the correct map for whatever game I'm playing.

EDIT: We posted at the same time DaveMMr.... I'm using Mame v.88 if that makes a difference. I copied and pasted what you have there into my mame.ini file and it made no difference.
Am I looking in the right place? It's a text file I open in Notebook just called "Mame" in my main Mame folder.