Just to clarify a couple of things (this got way long winded, repeats some of what I've already said but still please read it)
First I got the Core Multiplier on the E4500 wrong it's 11x not 9x my mistake, long day.

The stock Core Multiplier matters as you can't increase this on a Core 2 Duo only decrease it in steps of 1x down to 6x, so the higher the Core Multiplier the higher you can get the CPUs clock speed with and given FSB speed.
So if you want to hit say 3.6ghz and don't want to go any higher than a 400mhz FSB, because your using cheep DDR2-800 and don't want to overclock it , then you need at least a Core Multiplier of 9x to achieve this that CPU speed.
So why would you buy a E4500 with a multiplier of 11x when you could buy a E4300 with a multiplier of 9x would in thoery do the job? Well the answer is that the faster stock clock speed a CPU has the better binning it has, this mean the fastest model or a given series of CPUs will tend to have the highest overclocking potential. Any example of this is the E6750 with a multiplier of 8x @ 500mhz FSB it should be able to hit 4.0ghz but in reality they tend to hit a wall around the 3.8ghz mark with air cooling, as where the E6850 is know to be good up to 4.0-4.2ghz before it hits the wall on air cooling.
So running a E4500 @ 9x 400Mhz FSB is a safer bet to get to 3.6ghz (a 63% overclock) than an E4300 @ 9x 400 FSB to get to 3.6hgz (a 100% overclock).
When deciding on what FSB to run to achieve your final clock speed you need to think about what else your going to overclock then you increase the FSB, the FSB speed effect the speed of your CPU, Memory and Chipset, and these all need to be taken into account. The lowest FSB you can run is the Final CPU speed you want to hit divided by the stock Mutliplier of you CPU, for a E4500 @3.6ghz that is 3600/11 = 327mhz (1307 FSB), now 327mhz * 2.4 memory multiplier gets you DDR2-784 so now your memory is underclocked at there for you have less memory bandwidth, if you increase the memory multiplier to 2.6 you end up with your memory at DDR2-850 now it's overclocked, so the easy thing to do is find the common ground between your memory speed and the final CPU speed you want of 3600mhz with is 400mhz 2x for the memory multiplier to give DDR2-800, and 9x for the core multiplier to give 3.6ghz.
The one other thing you have to watch out for when selecting you FSB is whether your motherboard and chipset can handle the new FSB speed, now the P35 Chipset is good for well over 500Mhz FSB speed, but this is only on the right motherboard with good chipset cooling, some motherboard become unstable when you increase the FSB speed due to their design, others because the North bridge heatsink can not keep the chipset cool at the higher FSB speed. Also the higher you increas the FSB the more likely it is that you will need to overvolt the FSB and Chipset some to make it stable and the higher speed, that extra voltage equal more chipset heat.
Higher FSB speed give the CPU more bandwidth to talk to the memory and the rest of your system with, but there is limit to what is practical, an extreme setup would be run say a CPU at 6x 600mhz FSB to get to 3.6ghz, this would require a very stable motherboard with very good chipset cooling, and a lot of extra voltage to the chipset & FSB to work, it would give you massive FSB bandwidth but would be very hard to get stable.
Memory Speed & bandwidth why should you care?
Memory bandwidth is the speed at which the system can get information from your RAM, basically more is better as long as you CPU can put it to use, little point in having a 800 FSB CPU with dual cannel DDR3-1600 the CPUs FSB bandwidth is just now wide enough to make use of the huge memory bandwidth with would give you.
Memory bandwidth & FSB are important because of the way CPUs work, without getting into a whole heap of tech-talk, The great the Memory & FSB bandwidth a system has the more able the system is to supply the CPU with information to process, that catch is if you don't have enough memory or FSB bandwidth then the system has trouble keeping up with the speed of the CPU (this is made worse if the CPU is noticeably overclocked). This is why CPU have Cache Memory it acts as a buffer between the CPU and the system memory, hiding any gaps in the flow information from the CPU.
Now what happens if the memory bandwidth can't keep up with the CPUs needs, and the memory access is to random for the cache memory to buffer fully, then the CPU becomes starved or information and can't process anything for a split second, now it's worse than that because of the way a CPU works, what might be a one cycle break in the flow of the data can result in a 20-40 cycle break in the processing of data, so the penalty for not having enough memory or FSB bandwidth can be much great than you would think.
A modern Celeron is nothing but a Pentium 4 Core with 1/2-1/4 of the cache memory and a lower FSB, these two things make the same CPU Core perform much slower than it would in a Pentium 4 at the same CPU Clock speed because it spends so much more time wait for data to process.
This where memory & FSB speed & dual channel kick in.
Theoretical DDR2 Memory bandwidth:
DDR2-800 Single channel ~6.4GB/s (400mhz)
DDR2-1000 Single channel ~8.0GB/s (500mhz)
DDR2-800 Dual channel ~12.8GB/s (400mhz)
DDR2-1000 Dual channel ~16.0GB/s (500mhz)
800 FSB ~6.4GB/s (200mhz)
1600 FSB ~12.8GB/s (400mhz)
2000 FSB ~16.0GB/s (500mhz)
As you can see the drop from DDR2-1000 to DDR2-800 is only 23% but the Drop from Dual channel to single channel is 100%, this is why it's important to run dual channel, you loose way to much memory bandwidth if you don't run dual channel.
How does this effect MAME if you drop from dual channel to single channel, well very little at 500mhz (2000 FSB) DDR2-1000 with a E6850 with 4mb of cache like I'm running, about 2-3% across the board in fact as you can see in the benchmarks below.
The catch is that while MAME is basically CPU limited and doesn't appear to require huge memory bandwidth, these result are on my system and thus not the norm, the effect of dropping to only 6.4Gb/s memory bandwidth with a single DDR2-800 Dimm on say a E4*00 series with only 2mb CPU Cache will probably be much more noticeable that the effect of dropping to 8.0GB/s with 4mb of CPU cache on my system.Benchmark performed same as normal just with my memory in single not dual channel. (still 2gb of RAM in system)
ROM NAME MAME Ver dual Channel Single Channel
- 1942 0.121u1 6572.08% 6555.78%
- a51site4 0.121u1 235.35% 234.89%
- airco22b 0.121u1 143.19% 141.29%
- alpinerd 0.121u1 88.50% 87.20%
- biofreak 0.121u1 145.12% 143.02%
- blitz2k 0.121u1 160.68% 160.12%
- blitz99 0.121u1 153.09% 151.04%
- blitz 0.121u1 167.30% 166.52%
- calspeed 0.121u1 204.23% 203.53%
- carnevil 0.121u1 285.30% 283.93%
- crusnusa 0.121u1 276.53% 275.63%
- crusnwld 0.121u1 249.91% 249.36%
- cybrcomm 0.121u1 135.27% 134.07%
- Daytona 0.121u1 212.79% 209.73%
- gauntdl 0.121u1 134.20% 133.14%
- gauntleg 0.121u1 159.81% 151.36%
- gradius4 0.121u1 96.85% 96.45%
- hyprdriv 0.121u1 175.17% 167.02%
- mace 0.121u1 251.07% 248.84%
- offroadc 0.121u1 438.94% 436.40%
- propcycl 0.121u1 137.27% 135.14%
- radikalb 0.121u1 177.72% 176.58%
- raveracw 0.121u1 121.21% 119.77%
- ridgerac 0.121u1 151.72% 148.99%
- scud 0.121u1 28.61% 27.87%
- sfrush 0.121u1 211.70% 199.13%
- sidebs2 0.121u1 215.90% 213.46%
- speedup 0.121u1 179.16% 179.30%
- starblad 0.121u1 145.58% 144.87%
- surfplnt 0.121u1 163.14% 161.74%
- tenthdeg 0.121u1 85.30% 83.64%
- timecris 0.121u1 145.30% 148.09%
- wargods 0.121u1 411.74% 411.54%
- wg3dh 0.121u1 375.54% 374.59%
- xevi3dg 0.121u1 371.37% 372.76%
I am running the Rosewill Z-3 coolers I have 3 of these & they work great, the artic cooler you are looking at is fine. But with the tags on it, it makes it a pain to install these coolers are not good for being used over & over. That is why I like the rosewill or similar they use a back plate w/screws & nuts. I am kicking around dumping my 6750 & going to the 6850 just for the extra performance. I also prefer Gigabyte motherboards I have 3 of the GA-P35-DS3L, these boards are tough & great overclockers.
dm
I had a look at the cooler your using and while it's the right design type for overclocking it's only a mini tower-cooler, with only a 92mm fan and what looks like three heat pipes, I'd look at tyring something bigger like the Coolermaster Hyper 212 or the thermalright 120 utlra before you change to a E6850, I would be suprised if you couldn't get to at least 3.6-3.8ghz out of your e6750 with a larger heatsink and a bit of tweaking, presuming your ram is not what is holding you back.