Has anyone ever used one of these?
I've got an N50, but never could get used to it.
I play FPS games with the mouse in my left hand, and a 10-key in my right.
That provides the best feel to me, as I use a 10-key by touch, and the buttons are aligned "properly", rather than staggered.
The Nostromo devices are left hand only, and I just couldn't get used to mouse right, despite using mouse right for work, 8-10 hours a day.
Doom and Descent had a large impact on my play-style, and I used a joystick on the left for those.
When the mouse driven games began coming out, it felt much more natural to me to keep the mouse in my left hand.
I AM left-handed, which may have a large impact on that as well--although my Dad plays mouse left as well, and is right-handed.
That may be my fault for introducing him to all those games, using my pre-set player profile though.