I did try a couple, but there are few keys on a standard keyboard that games don't override. One of the apps even rendered my regular keyboard useless. Took nearly an hour to fix it using the on-screen keyboard. The only button that worked was the key I programed. I am going to try using different drivers to see if I can fool it into working. I know that works with my wheel (if you force drivers to be a Logitech, it works like a Logitech). Tho I am sure that is something they did on purpose. Worth a shot, we'll see.