My wife like's playing my MAME cabinet, but I agree--she would have never thought of making one. In fact, she would have never thought of using the software in the first place.
I think women are more of the "take it as it comes" type. If there were MAME cabinets for sale at SEARS, there might be some women interested in getting them. But I think it's more a man's thing to build stuff and tinker around with stuff.