Waterjets are pretty slick. I didn't know they used them for food!
In response to the OP: I will agree with bkenobi when he said that at prices like that, you're best off trying it for yourself. A pilot hole and a holesaw, with the plexi clamped onto scrap wood. I think there is more in the woodworking forum; some people suggest sandwiching between two pieces, etc.
If you're doing more than just cutting button holes, though, such as cutting curves around the corners, I'd suggest doing more research before attempting it. At any rate, $225 is WAY too much for a piece of plexiglass. I'd almost bet you could get a piece of actual GLASS cut for that much (but don't quote me on that).