I use a JPAC (or an IPAC) which you can have 'shift' button options. You press the 1UP button in combination with another key to do this.
Outside of a hardware solution, i'm not sure how easy it would be to do this. You may be able to set a button as an ALT or CTRL key, and use a combination of buttons to do what you want. Although you can run into some problems if you still need the button for gameplay (as ALT and CTRL are common for windows shortcut keys).