If you wait til tonight, I can snap off some pics of my setup, which is exactly what Severdhed said. I have my controls wired up to a 25 pin serial connector, then I have a set of hacked DC pads with wires coming out into the connectors, and I have an Ipac coming out to 2 serial connectors. Keep in mind that I use a switch box for every player, so that makes them 2 total. The system works great, and all that is needed is to flip 2 knobs that I placed on the side opening of my coin door to swtich between DC and the PC.
As for the display, I have no idea about the light guns. I guess if your monitor is picky you might need the amp, but you lose nothing by trying it out without it first. About the sync, I have a presentation monitor capable of 15khz, and it has the old twist on connector cables with separate syncs. Lemme look in there later and I'll double check to see what I'm running.