Mouse autoscrolling

[TexFlood]

I'm starting to wire my control panel and I have a mouse problem that I can't quite track down, and was wondering if someone has an answer for the following issue:

When I open the GameEx FE and put the mouse over any of the menu options it runs down through the list of menu items to the bottom of the list.  Wherever I mouse over in the list of menu items it always runs down to the bottom of the list.  It has worked before but this problem keeps on coming up...  Is this an issue with USB?

Edit:
To add a little more detail, I am using the following on my CP:
U360 joystick with USB connection
Happ 3" Trackball with USB connection
TT2 Spinner
USB mouse

The USB items are attached to a CyberPower 7 port USB hub that is connected to a USB 2.0 PCI card.  I don't know if it matters, but the 2 built in USB ports on the computer are USB 1.1.  I don't use those for anything.