Some thoughts. Yes, I know this is a MAME board so please don't flame me!!
An original Galaga board has been mentioned a few times. That is a good option other than they tend to be a little flaky at times. They are like what, over 20 years old. From memory I want to say a Galaga has a lot of proprietary IC's and some odd power requirements. Not odd voltages but more like issues with voltage drops across the board set. I have never owned one, all this is based on reading about repairs and t-shooting.
Beyond that, how about a multi-JAMMA, like a 39 in 1 board? They seem to be getting rather inexpensive. You can turn off all the other games and it will boot directly to Galaga. With just a single game "on", like Galaga, it will only show that game's demo screen. When you coin it that single game starts. No drop back to a menu to make a selection like it would with more than one game on. JAMMA wiring so that is straight forward, direct compatibility with arcade controls, straight hook up to a 15mhz monitor (not sure what you were looking to use), and all solid state. No drives to fail, no noise, little to no heat issue.
Just a thought. Good luck and post pics!!
brent