110,000 BTU? Whoa. I was thinking about getting something around 14k or 24k.
That would probably be fine for a one car garage sized room. When I got my heater, I had the garage and a Florida room that is becoming my gameroom. With the door from the garage to the Florida room open, it was an area larger than a two car garage to heat. Last year, I added a 3rd zone and baseboard heat in the gameroom to-be, so the heater is now a bit overkill. One benefit is that it heats the single garage up really fast. The main downside is that the fan is noisy on it.
If you have short spans of time to work, or have kids and just have to take time as you can get it, the nice thing about the large heater is that it will heat your workspace fast. The other cool thing is that if I'm working on a car in the driveway, the heater is powerful enough to hit you with warm some warm air outdoors from 20 feet away.
This is the style of heater I'm talking about in case someone isn't familiar with them. I'm sure it doesn't make sense for everyone, but I've had mine for 4 years and I love it.