Hey guys,
Thanks for the posts and additional info.

Lexan was bought Saturday night, and yesterday most of the afternoon and evening was spent working the cuts.
I am amazed at how easy this was, although it took a boat-load of time to finish as I was really careful when making the cuts - 1 messup and the whole piece would have been wasted!
A must is to get a test piece of lexan and use various cuts. This is the only way to see how to set depth on the router, and work with different bits.
Tools I used: Hand-drill, Router, Clamps and Bricks to hold stuff down
Bits for the router: two types (a) 1/2" V-Groove bit for the corner counter-sink holes and (b) 1/8" Roundover bit for the straight cut edges
Bit for drill: (a) 1 1/8" Forstner Bit for hole cutes - this is a must and worked great
Here are some pics of my success.

David