Drilling holes in Perspex. Spade bit or holesaw?

[londonbabe]

What's better for neat holes in Perspex/Plexiglas? A holesaw or a spade bit? This is for the buttons and joystick, obviously.

[NightGod]

Forstner bit to get things started, router + flush trim bit to size.

[Xiaou2]

Forstner = cleanest.  best to use with a drill-guide as far as i recall

Spade next = and very fast.. yet will need a drill-guide to use without crackage

Holesaw may roughen the edges slightly, but they can be used without a drill-guide. 
they also seem to be best for not cracking plexi when used in a good manor. 
A light hand sanding on the hole edges should clean up any burrs. 

[ahofle]

If you go with a spade bit without a press or guide, use it at a high speed with minimal downward pressure (that's what causes the cracking in my experience).  If you press lightly and put the drill on the highest speed setting, it will start to melt through the plexi and you'll get a nice clean hole.  Definitely practice a few holes first on spare piece to get the hang of it.