There's been a lot of talk of dual Led-Wizes. Do a search and you'll see some threads on the topic.
Randy alluded to the possibility that after the current software update, he will work on supporting multiple devices. In the meantime, Powermame can handle multiple Led Wiz devices. This won't help in LED animation though.
Incidentally, I have two Led Wiz devices (one and two) and about 14 buttons that have RGB LEDs. What I'm doing is mapping using the first Led Wiz for the Reds and the Greens (or Blue - haven't decided yet - but definately Red) and then the final color will be handled by the second Led Wiz. This way, I will still have the animation - and Powermame will take care of any button - or trackball - that needs to be blue for whatever reason I come up with.