I just revamped my whole system and am now running with a WG K7400 monitor and an ArcadeVGA card.  (I had a K7500 and Blade T64.)  I'm running ArcadeOS and DMAME 0.65.
Everything in DOS looks great, ArcadeOS looks great (but does not fill the whole height of the screen), but I get a ton of flicker when I run almost any game.  Also, the sizing for the vertical games is all off.  I copied the ArcadeVGA MAME.DAT file into my ArcadeOS directory.
Do I need to select resolutions for every game before I play it?  If so, when I go into the game config in ArcadeOS the only option I have is to hit Start 2 to close.
One other problem - I often get a lockup or repeating sound when I exit out of a game while it's playing audio.  I didn't have this problem w/ AdvMame.
Any ideas?
Thanks.
 - Dave