I have to agree with VRF.
Although, depending on your setup just having two rear fans blowing in might bring down the temp enough that it wont matter. A big part of the heat in the case would be the overall airspace available.
If you want all things on the rear, and want to do both in and out, your best bet would be to have the intake at the bottom, and the exhaust higher up. Since hot air rises, it would result in better exhaust of hotter air, and the cooler air would hit your components directly.
and you could put in a baffle type thing (board) above the PC components and intake, forcing the air to take a path past the PC, and around to the exhaust. Although now your just going overboard.
As for dust, put a few mesh filters over your fans and clean them every 2-3 weeks. It'll keep dust to a minimum inside...though it won't make it perfect. If you just do exhausts, your going to get dust also because you create negative pressure inside the case/cab and it will suck air in from wherever there's a gap in the case - and with it dust.
