The way I made mine, I used cleats all the way around the edges of the sides. I cut both sides, then connected all the cleats. Each cleat was the same distance in from the edge of each side. Then I mounted a couple of front and back panels (and/or top and bottom) to the cleats to ensure that both sides were aligned and square.
If your framing connects to the sides, you can likely do something similar. Connect frame members to the sides first before you go and span the distance between sides.
-pmc