I just built some bookcases with oak covered 3/4" MDF ($35 a sheet!!!)
THIS STUFF SPLITS like you won't believe!
*** PRE-DRILL EVERY HOLE -- ESPECIALLY if you are are going into an edge and not the flat surface. *** Also.. keep away from the last 3" before a corner if drilling into an edge.
In creating the bookcase, I used wood dowels and drilled holes for them on all the visible surfaces, but figured I'd save a LOT of time by simply screwing the base into the 4 uprights (it was a 8' wide bookcase with 3 shelf areas), since the base is against the floor.
I was at least smart and pre-drilled all the hole on the base (that I was drilling through the flat surface) and even got a countersink bit to make the screwhead flush. I used 1 5/8" Sheetrock black phosphate screws.
However, I forgot to predrill into the uprights, and after screwing in about half the screws, I paused and could literally hear, for about 5 minutes, the MDF splitting up the edge I screwed into!

One is really bad and split up about 3" from the edge (only 1" of screw was in it). It's easily 1/16 to 1/8" inch split against the edge. The others are about 1/32nd of an inch wide for about 2" up.
To fix it, I did 2 things... First, on the side that split the worst, it was to be up against a wall, so I was able to drill in the side and then put a short 1/2" screw in and help "pull" it back together. Plus that and all the others, I squeezed as much wood glue in as I could to keep it from splitting more.
Last nite I started nailing on the 1/4" oak backing sheets. Even a super thin nail from a nail gun, (1" nail length) caused the dang MDF to split when nailed dead center in the edge. However it was just a hairline crack running 1/2" either side of the power-driven nail. (The nail wasn't much bigger than a large needle..we're talking small)
So I learned my lesson. The next time I build bookcases, I will either:
- Peg the entire thing or at least pre-drill into the uprights. (and just deal with the nailing doing small splitting)
- Get oak laminated PLYWOOD to build the frame with, and then just use MDF as the moveable shelves (since it doesn't bend as much as plywood when cut with a small depth like a shelf)
Therefore, since I havn't started building my cabinet(s), I have leared a lot from the bookcases. MDF is a great product, but you HAVE to treat it correctly, otherwise it can be much worse than even particle board (heck, it's the same thing, just finer particles)