The interference could be getting into the speakers at any point in the audio cable coming from the pc.
Try and move the cable around to see where the inteference is coming from - it be the tv, but it could also the tv's power supply cable. (although this would more likely sound like a 'hum'). If you are using standard computer speakers, you are probably just using standard 3.5mm jacks and standard cable which is quite susceptable to interference (professional audio installations would use balanced audio cables, which is very good at removing interference picked up in a cable).
So:
1) try moving the audio cable away from the tv/other cables. Ideally you want to give it its own 'route' to the pc away from power cables etc...
2) if its the actual tv itself directly interfering with the speakers, you may find placing a sheet of metal (eg from the side of an old computer case) inbetween the tv and the speaker might help.
If nothing helps, then it could be that the interference is being introduced in the soundcard on the pc - is the pc in a closed case? Does shielded the pc help? etc...