Well, this is just my own opinion, but...
I think 22awg is fine for everything. I can't imagine why any considerable amount of current would be flowing through your input lines which would require something "thicker" than 22awg. It shouldn't take much to sink the input to turn it "on".
Also, I would stay away from solid core wire. It can get very brittle, or get stress fractures in the conductor. In other words, it would tend to fail more often if you were thinking of interchangeable control panels where the "plug" gets attached/re-attached often.
As far as using the stranded 22awg for d-sub connectors, I say "practice makes perfect". I've got 20 years soldering experience, so maybe it's easy for me to say that, I dunno.