I have played at my Midway Gorf cocktail for hours at a time without issue, it is a vertical one, no 3rd control panel. No issues at all.
Also, I love arcade games, but I will very rarely put in an arcade playing session longer than a half hour or so. The main exception would be Robotron (and NEITHER ONE of your wrists is getting any support in Robotron).
If there is any "issue" with cocktail games it is how you usually end up bent just slightly forward while playing, at least I do, but it could be that I picked my chairs for it because they had real 1980 flavor, and not because they were good cocktail chairs.