Some people have problems getting into safe mode using F8.
Here's an alternative method.
1. Click Start
2. Click Run
3. Type msconfig in the textbox and press ENTER
4. Click Boot.ini tab
5. Click /Safeboot option
6. Click OK and reboot
You will reboot back into safe mode. Once you are finished, reload msconfig and do the following to get back into regular mode:
1. Load msconfig (as above)
2. Click General tab
3. Click Normal Startup
4. Click OK and reboot