(I lost my job recently which always gets my brain overexcited and I started reading though old journals of mine and it's gotten me to thinking...)
A friend of mine has no bones or muscles and is just a pile of goo and it makes him very frustrated to watch me kick so much a** at Ms. Pacman.
How difficult would it be to find an unused portion of the brain - just 4 binary outputs that could be interfaced to a computer so that one could play Ms. Pacman with Mame just by thinking? I suppose there might not be too many biologists/neuroscientists around wasting their time building arcade controls, but it's worth asking.
I see stuff like this on slashdot.org or in wired (dead tree) all the time... (BTW does your friend like being called a "pile of goo" ?)
Where they use something that looks like colander (think rick moranis in the original ghostbusters) and a bunch of wires and the subject was able to "learn" how to focus his "brain waves" to initiate typing/or move a mouse cursor...
There are also specialized controls out there if he has SOME motor skills. sorry no links handy... but their are apparatus for interfacing with a computer that uses eye tracking... or possibly a "mouth stick" which I think uses suction to steer wheelchairs...
I apologize for not having direct link but there is stuff out there... but it may not be cheap... but maybe it can be bought at a discount or as a medical device if it's multipurpose (a general computer interface that also gets some use in MAME)
maybe if you google searched slashdot site with the "right" keywords you could find something...
goodl luck!
rampy