The best setup against spyware and virus, mine

I prefer mozilla over firefox. I have too many problems with firefox for me.
Anyway, I use Eudora for email, Mozilla 1.7 for web browsing. Installed google toolbar in IE. Have AVG, Spybot S&D, and Ad-aware.
I haven't had a spyware or virus since I have had this setup

I also think Mozilla is far better than IE for web browsing. It adhere's to the CSs and xHTML standards better than IE. Tabbed browsing is the only way to go. I can't stand IE now that it doesn't have tabbed browsing.