Well considering I'm going to have a yoke and a 360 degree wheel, occasionally changing things manually will be unavoidable.

I could change modes via sending a serial command, but that's probably more trouble than it's worth. I'm not sure about what I'm going to do with the led controls yet.... I might have them running with the keyboard on the same teensy, but then again I have a ledwiz collecting dust..... it seems a bit overkill for this project though.
I'm not a huge fan of the shift buttons. I always forget the combos I setup. I always remember escape and pause, but anything I don't use too often ends up a mystery.
I was just thinking that it could default to the arrow keys, but maybe have r,f,d,g as a second, the maintenance buttons as a third (f2,f3,9 and tab), and something else as a fourth. I would rarely ever use the others, but when the need arose I wouldn't have to whip out a keyboard.
Yeah I'm pretty sure I want dedicated escape and at least one radio button. I'm just trying to figure out how to do a nice layout. I still haven't given up on the analog touchscreen idea either. I do have some psone screens lying around somewhere.