Sure thing.
20 speakers? Are you using the 70V distribution or the E taps to power all those speakers? I'm not an amp or speaker expert, but I do know that serious problems can arise if 20 speakers are connected to the E taps in the jukebox, especially if they are wired in Parallel. In Parallel, the impedance would be so low that the amp will probably blow. If in series, the impedance would be so high the speakers would sound really bad.