Something that works really well with MDF is to mix up a batch of wood glue and water then brush it on to the rounded edge. Really saturate the edge. Once it is dry, it is a nice and hard coating that you can sand if need be.
That is a great idea Slippy. It would be like sealing the edge and the MDF would just soak that up. I'm going to remember that one.
Not my idea. I wish I could remember who first posted it. He called it "armoring" the MDF.
I have personally tried this water/wood glue method to "seal" a rounded corner. I wish that I could say it worked... but it didn't. I was told to use a 50/50 mixture of water and wood glue but that turned out far too liquidy.
Perhaps I got the mixture wrong or did something else wrong but it literally didn't seal the edge at all. If anything, I'd say only add enough water to barley thin the mixture enough to spread it.
However, what I found to work FAR better was simply spraying the rounded edge with KILZ oil based primer a couple times and then sanding it smooth. When done, I couldn't tell the difference between the rounded edge and the pre-finished flat surface.
Slap on some polycorbanate coated artwork and that control panel will last a long, long time.