For that large amount of buttons I wouldn't recommend it. Remember each direction (P1 up, P1 down, etc) is a button as well. I have the mini on a 2 player arcade with 6 buttons per player, two sticks, two coin buttons, two start buttons, and escape. It was hard to avoid using buttons that Windows uses for other functions/shortcuts like Q, Esc, space, etc. You're kinda limited!