I have no idea.

depends on how they've done things.
also, if you post what the ORIGINAL board is/was perhaps you can find another to replace it with. I think you are going to find you are going to have to stay in the same era of board (IE you arent going to replace it with a brand new modern board.) because the software is likely designed for the board and it's specific chipset/audio/nework etc.
depending on how theyve set things up on the harddrive, you MAY (but unlikely) be able to swap out the board and just patch things up in the OS to get it to run. but without knowing more, it's hard to tell.