And some games need something else pressed at the same time as the F2 button. Those game might be listed in the
mameFAQ. If not, you can usually find notes in the source, and
sometimes at
mametester's Dip switches, orange file, or BTANB.
At least one used to need to hold down the F2 button the whole time, but not sure if it's still that way. (Original must have been an on/off switch.)