Yeah, it can be done but it's just not quick or precise enough. Try playing Avalanche with a trackball--it's just too sloppy to be any fun, IMO.
You can but I tried it and it's not as satisfactory. I've taken on the opinion than a spinner is more valuable to a panel than a trackball (game-wise) at this point (and not as needy for space.)
Just curious--why do you say this? I was contemplating putting a spinner on my next project since my first project has a trackball and it would be nice to explore a new control type, but I'm struggling to come up with uses for it. I'm not terribly excited about spending $100 (or whatever it costs) on a piece just so I can play Tempest and Arkanoid. The trackball, on the other hand, gets me Missile Command, Marble Madness, Centipede, Wacko, and great "party" games like Golden Tee, Shuffleshot, Shuuz, and WC Bowling.