Ummm, I would not use any spikes! A speaker stays in place. But a cabinet will be rocked... and when that happens.. it will tear up the flooring like you wouldnt believe.
You probably are using an LCD for the display. Typical cabs used CRTs, as well as much more wood, due to the needed depth. This mass was far more than enough, typically, to hold the cabinet in place.
A person putting their body into play.. can easily get a 200# force output. Add 2 players.. and you might even double that.
The best thing you can do, is to get some metal weights... or bags or sand / gravel at the home improvement store.. and place them in the bottom of the cab.
The only other means of dealing with extreme forces, is by direct connection (bolting to the floor), or by absorbing forces... such as a CP that has the ability to move an inch or two in any direction, with a foam/spring absorbing material... and possibly the cabs bottom, having a counterweight and tilting pivot system, with that same shock absorbing material.