Re: JAMMA set up -- what BobA says -- follow Bob Robert's guide and you are good.
Re: 60-in-1 -- most of what Paige says. I got rid of my vertical MAME machine and replaced it with a 48-in-1 cab for 4-way (and 2-way) games and a 60-in-1 cab for 8-way (and 2-way) and trackball games. There are some annoyances, particularly with some sounds, and the fact that neither board has Blue Print, but was well worth my time and money to make the switch. Those two cabs get played more (by "normal" people) than anything in my home, except for the NeoGeo (which always seems to get the most play, for some unknown reason) and the NAOMI (daughter loves the Sports Jam, again, for some unknown reason).
In my experience, folks here don't hate the xx-in-1 boards for the unlicensed ROMs, but rather for the blatant ripoff of MAME. When I bought my xx-in-1 boards in the past, I made donations to the dumping project and cleared any doubt from my conscience.