That's one of the reasons why I favor modular over other types. You don't have to make any comprimises, you can easily have the right controls for every game. Even control combinations as odd as Tron, or button patterns as weird as Defender/Stargate. I even have a diagonally mounted 4 way just to handle Q-bert and Congo Bongo correctly. If you use a patch panel, you can even keep lighted controls with ease.
I'm just really surprised that no one's mass producing these things. Seems like a surefire winner to me.