Generally it will have a plastic/paper sheet stuck on both sides- leave this on until you are 100% done with working on the acrylic, as it scratches super easy, and is a dust/particle magnet. First, make sure all holes (including the screw holes that will retain the acrylic) are drilled in the wood or metal or whatever is the base of the CP. Then sandwich the acrylic between a scrap piece of wood and the control panel body, using the existing holes as guides. As has been mentioned, it is the drill pulling up/down that is likely to crack the acrylic. If you use clamps, sandwich it between the wood, and go slow, it should be fine (I just used this method the other day, and I was freaked out beforehand- but it worked fine).