i'm not sure what the exact thickness of the plexiglass i used on my panel, it was just under 1/8" thick, on top of my 5/8" MDF. it is held down with nothing but the buttons. the Tmolding covers the edges of the plexi and it stays in place very well. if you are going to have the plexi sit above the tmolding, then you may need screws/bolts to hold it down at the edges