you'd be surprised at how much USB powered speakers can blast. I got a set from a local surplus (they were on liquidation) and I was thinking of using them on the go, but powerfull as it is, I will keep them as a main source of speakrs for the PC.
On my cab, I go a totally opposite route as you. I want the PC in the cab to remain powered. But I modified a power bar to run from the switch on the top of the cab. This powers the marquee, monitor and speakers. So I can leave the cab "off" and still have computer activity.
One could power the whole PC this way too.