Not flaming you here, but please take about 5 minutes and read the accompanying readme that comes with the program..... I set this up yesterday for the first time, had a little bit of trouble, and lo and behold upon reading further it tells you how to set it up. Within 15 minutes I had it set up, with a new skin even.
Just looking at your file, you have no path to your roms, dat, or catver for starters....