Another thing to consider is if you want positive or negative air pressure ... that is, the fan blowing cool air in or sucking warm air out.
With negative pressure, unless your cabinet is sealed nice and tight (except for fresh air intakes at the bottom rear of the cabinet), dust will build up around anywhere air can find it's way in. ie: around the monitor bezel, marquee, coin door slots, etc.
If you have the same number/type of fans blowing in the bottom and sucking out the top, then the pressure in your cabinet will be balanced and dust will only gather in the path that the air flows. (and onto components it flows over/around).
Steve