Honestly.... it doesn't matter how you transport an arcade machine, standing up, laying down, on it's back, on it's side, whatever and however you get it from point A to point B the same rules apply.
Check for loose parts and items before loading.
Pad to prevent dings , nicks and scratches.
Strap it down.
Check it
all again when you set it up at it's destination
before powering on.
When in doubt.... call in the professionals.
