Well, AdvanceCD discovered all my hardware, and made a nice little playable thing.
I couldn't get Killer Instinct 1 or 2 to play, but I suspect that's because I may be using incompatible versions of Mame/ROMs.
AdvanceMenu is interesting, to say the least. It doesn't seem exactly cab friendly.
But this was all running under Linux. I haven't tried AdvanceMame on here yet. The last few times I played with it I got nothing but garbled graphics onscreen. And I played with it on a couple different systems, and on an arcade monitor.