Do you mean that you want to use one computer to run independent hyperspin instances on both monitors?
With Windows, you'll run into more frustrations than you might initially expect because of screen mode changes, exclusive full-screen modes, active window limitations, and single-instance program design.
If you just mean that you want to be able to switch the video between the two without cable swapping, that's possible with Windows 7's displayswitch.exe, NirSoft's
nircmd setdisplay, or 12noon's
DisplayChangerYou can also clone your display output to both monitors using those programs, or, if both monitors are hdmi and have the same native resolution, you could use an hdmi splitter to clone the display.