You should be able to get black, white, clear and opal(translucent white) in lots of thicknesses. I have all of those in 4.5, 6, 10, 15, 20 and 25mm thick. Black is the only one that is truly opaque.
I have access to one blue, one red and one yellow acrylic thicker the 3mm. Even then, those only come in 4.5mm. I do know that thicker coloured materials are available in Europe. None of this is any help to you...
Laminating is an option. There are special laminating solvents for acrylic.
What exactly are you trying to achieve? If you paint inside the holes, the clear can be secured to the panel from underneath without disturbing the paint finish