I know this wasn't directed at me, and I am but a solder knave, but I'll give my two cents. Tips will last for years and years if you take care of them. I was always taught to let a blob of solder stay on the tip when you were done to protect it from oxidation. Honestly I keep lots of different size/shapes of tips in my toolbox but I've never had one go bad*... at least not since I screwed one up back when I was a co-op many years ago...
*caveat... there was a period of a few years when I was away from engineering so some of my tips have only seen very light duty...
Tips for tinning... If they're stranded wires I was taught to not pull the insulation off all the way to start with when stripping them... leave it on just a little bit and use it as a handle to twist the strands nice and tight before you pull it off the rest of the way. If you don't have good rosin core solder put a little flux on your wire first. Put your wire in a "third hand" thing or some other clamp or what have you, or set it on the edge of the desk or something. Solder in one hand, iron in the other. Get a little dot of molten solder on the tip, it helps with heat distribution. Bring the tip and solder blob into contact with the wire, watch with satisfaction as any rosin you applied sizzles up, and the wire should basically suck up the solder blob as you hold it there. Bring the solder in your other hand into contact with the wire, iron still touching the wire, and move the iron back and forth a little to make sure you wet the whole tip.
As for the fumes (more concerned about rosin fumes than the lead vapors personally), some people use a fan to blow them away, or you really can just take a deep breath before you touch the solder to the tip then blow it away from yourself as you go... just come up for air from time to time...
