Thanks guys,
I must have worded my post strangely, for starters I'm NOT having problems with command line Mame applying filters - it's the video card! In fact the card does it with every emu fullscreen pretty much and I've seen other nvidia cards do similar things on friends pc's.
I wanted to know how to apply the D3D filters to rectify the blurriness

I will go read up on that one.
I'm in the process of picking out front ends for the cab (mame32 is fine for a pc, actually pretty good IMO - but not for a cab) and want one that will let me do this easily. I don't wish to enter a command before every game.
Just had a look at Mame Menu and loved it's simplicity, only prob was when I pressed escape in game it went right back to the desktop. Mame Menu was still open, but minimized and ugly looking, not hiding the windows environment like it should. Anyone know how to fix that too?
As for MameWah which so many around here like, it always freezes up when refreshing the rom list, I've never got it or Game Launcher to work. GL Keeps saying "Not Reading Drive D, Abort, Retry, Fail?" when I use mamescan. A shame, 'cause I really like it's look the best.
If I don't get a good one soon then I'll have to keep waiting for "Coin Be Gone" to be completed.